Originally Posted by Varius

Again, my first answer is always go custom, but here are some options for small mailing list management I would recommend:

Qmail + Qmailadmin

Qmail + EZMLM

Postfix + MySQL/PostgreSQL

As far as 3rd-party softwares the ones I have used (mostly PHP/MySQL ones out there ranging in price up to few hundred dollars) have been full of bugs and usually their support was very weak, so I don't recommend any.

Generally, every server I have ever configured I have used either Qmail or Postfix on, so most of my experience is with these two softwares. I do not recommend using the OS default Sendmail. If you are in a Windows environment, though, I'm not the right guy to offer advice as I stay away from Windows as far as mail servers go.