01-23-2013, 05:34 PM
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Too lazy to set a custom title
Industry Role:
Join Date: Oct 2006
Location: Earth
Posts: 30,989
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Originally Posted by newB
There have been several flu pandemics, but the Spanish flu was the most fatal in recorded history.
I would say the blame probably lies with the particular strain (H1N1), though other factors that reduced the populations ability to cope with infection (such as access to clean water and balanced nutrition) may certainly have played a role.
Just as this years flu appears to be more lethal than last years, though environmental factors appear to be relatively constant.
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In 1957, worldwide surveillance for influenza was less extensive than it is today. However, attentive investigators in Melbourne, London, and Washington, DC soon had the virus in their laboratories (7
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uhuh
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Most remarkable was the total failure of vaccine containing a 1943 H1N1 strain (effective in the 1943?1944 and 1944?1945 seasons) to protect the large number of US military personnel who were vaccinated.
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hmmm
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high-yield (6:2) genetic reassortant virus (X-53) was produced and later used as a vaccine in a clinical trial in 3,000 people. An even higher yielding HA mutant virus, X-53a, was selected from X-53 and subsequently used in the mass vaccination of 43,000,000 people. (I was a member of a Center for Disease Control advisory committee and an ad hoc advisory committee to President Gerald Ford on actions to be taken to protect the American public against swine influenza.) When no cases were found outside Fort Dix in subsequent months and the neurologic complication of Guillain-Barré syndrome occurred in association with administration of swine influenza vaccine, the National Immunization Program was abandoned, and the entire effort was assailed as a fiasco and disaster.
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actually this was a great read.. thanks |
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