The best programs for what you are doint are
Ero-Advertising, and
Plugrush.
It is also important to have a mobile version of your site, and use programs like
Bitter Strawberry, and
Sex Goes Mobile, which are very good for making money with this.
If you are good with the two above, you can start experimenting with
First Mobile Cash, and
VPS Mobile, if your sites are more specialized.
Other than that, you may want to try
Tube Ace for Wordpress, too. I've been making most of my money with this, but you need large networks of sites.