If you are using Varnish you are caching pages -- and taking up space -- see if you can purge the pages little used on a daily basis?
If you request images from other servers you may have slow page load times depending on the number of images requested, the geolocation and peering to your server(s) and the current load on the server you are requesting images from.
Fewer images per page might help. Using jQuery lazy load in your HTML might help also. The initial load time should stat out better.
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