Science: Drugs that are fun and make you happy may help cure depression

[uno]

No shit, right? Who would have guessed? Shockingly this is not an article from TheOnion.


http://blisstree.com/feel/ketamine-d...treatment-671/

Ketamine Nation? Special K Works Better Than Prozac At Treating Depression

The war on depression is getting mighty weird these days. Last week, scientists said psilocybin, the active ingredient in ?magic? mushrooms, could be useful in treating depression. This week? Beat the blues with ketamine! The drug?also known as ?Special K??can lift even suicidal depression in just a few hours, researchers say.

Ketamine is approved by the FDA as an anesthetic. It?s mainly used as a horse tranquilizer, though it can be used to sedate both people and other animals. It?s also used by people recreationally, and is capable of producing hallucinations. I had friends who got really into its use in college (between this study and the mushrooms business, my college friends should have been the least depressed people ever ?). Mostly, the high seemed to invoke a lot of sitting around in a silent, dazed stupor and occasionally falling into ?K-holes.? It didn?t look like much fun.

But ketamine could be really beneficial for treating major depression, according to some doctors. It works much quicker than typical antidepressants, which take weeks or months to really make a difference. And it could work for people whom typical antidepressants haven?t helped. Why? Carlos Zarate, a brain researcher at the National Institute of Mental Health who is studying ketamine, told NPR that depression is like a leaky faucet in the brain.

There are different ways to stop the leak, he says. ?You can go straight to the faucet and you can fix it,? he says. ?Or you can go to the water plant and shut down the water plant. The end result will be the same.?

The current antidepressants act in a way that is like shutting down the water plant, Zarate says. It takes a long time for the water to stop flowing through the miles of pipes that eventually lead to the leaky faucet.

He thinks the reason is that these drugs act primarily on the brain chemicals serotonin, norepinephrine and dopamine. Ketamine acts on a chemical called glutamate, which is much closer to the problem, Zarate says.

That?s nice, but ketamine can come with side effects that make antidepressants look like aspirin. These include urinary tract problems, hypertension, nausea, nightmares, memory problems and hallucinations. Zarate said because of troubling side effects, ketamine is unlikely to become a common depression treatment in and of itself. But understanding how ketamine works at treating depression could allow scientists to develop safer drugs that work in the same way.

A few of these drugs?scopolamine, which is used to prevent seasickness; a pill called riluzole?are already being tested on depression patients. Both of these drugs also affect the glutamate system, though researchers aren?t quite sure how. But one patient who took part in an NIH trial of scopolamine said:

?There?s no doubt in my mind [that] however it works or whatever receptors in the brain it works on, absolutely it has nailed exactly where my imbalance is.?

While it?s unlikely you?ll be filling a Special K or ?shroom prescription any time soon (darn!), it?s pretty cool that researchers are using studies of these drugs to find new, safer and more effective ways to treat depression.

[porno jew]

also the first brain scans of someone tripping on shrooms have been done and are using them to treat depression. i wish i had some k right now.

[uno]

Originally Posted by porno jew

also the first brain scans of someone tripping on shrooms have been done and are using them to treat depression. i wish i had some k right now.

Shrooms are also great for migraine/cluster headaches, OCD.
Ecstasy is amazing for a wide range of things including PTSD and acceptance of death in late stage diseases.
Ketamine helps with pain relief, depression.
Some of the greatest discoveries in history came while under the influence of LSD.
Weed helps tremendously with appetite, insomnia, nausea and pain relief.

Seems to me, someone should crush all those up, put em in gelcaps and you'd have one hell of a party/all-purpose-cure.

[Major (Tom)]

Originally Posted by uno

No shit, right? Who would have guessed? Shockingly this is not an article from TheOnion.


http://blisstree.com/feel/ketamine-d...treatment-671/

Ketamine Nation? Special K Works Better Than Prozac At Treating Depression

The war on depression is getting mighty weird these days. Last week, scientists said psilocybin, the active ingredient in ?magic? mushrooms, could be useful in treating depression. This week? Beat the blues with ketamine! The drug?also known as ?Special K??can lift even suicidal depression in just a few hours, researchers say.

Ketamine is approved by the FDA as an anesthetic. It?s mainly used as a horse tranquilizer, though it can be used to sedate both people and other animals. It?s also used by people recreationally, and is capable of producing hallucinations. I had friends who got really into its use in college (between this study and the mushrooms business, my college friends should have been the least depressed people ever ?). Mostly, the high seemed to invoke a lot of sitting around in a silent, dazed stupor and occasionally falling into ?K-holes.? It didn?t look like much fun.

But ketamine could be really beneficial for treating major depression, according to some doctors. It works much quicker than typical antidepressants, which take weeks or months to really make a difference. And it could work for people whom typical antidepressants haven?t helped. Why? Carlos Zarate, a brain researcher at the National Institute of Mental Health who is studying ketamine, told NPR that depression is like a leaky faucet in the brain.



That?s nice, but ketamine can come with side effects that make antidepressants look like aspirin. These include urinary tract problems, hypertension, nausea, nightmares, memory problems and hallucinations. Zarate said because of troubling side effects, ketamine is unlikely to become a common depression treatment in and of itself. But understanding how ketamine works at treating depression could allow scientists to develop safer drugs that work in the same way.

A few of these drugs?scopolamine, which is used to prevent seasickness; a pill called riluzole?are already being tested on depression patients. Both of these drugs also affect the glutamate system, though researchers aren?t quite sure how. But one patient who took part in an NIH trial of scopolamine said:



While it?s unlikely you?ll be filling a Special K or ?shroom prescription any time soon (darn!), it?s pretty cool that researchers are using studies of these drugs to find new, safer and more effective ways to treat depression.

K eats your bladder & kidneys & ut
ds

[uno]

Originally Posted by DukeSkywalker

K eats your bladder & kidneys & ut
ds

Yeah I saw that on National Geographic's Drugs Inc. about K. Out of tons of people i've known who have used/abused K prolifically none have mentioned any of those side effects. The guy they showed seemed to use way above and beyond anything remotely recreational.

[woj]

What does it feel like? Doesn't ketamine launch you into hyperspace at even mild doses?

[porno jew]

nah at mild dose feel spacey, trippy at higher doses hard to explain.

[epitome]

I would say I was happier when I was doing K and E every weekend. My Social life was also better.

Now I am lame.

[Shotsie]

K is fucking nasty. I'd rather be depressed.

[epitome]

Originally Posted by uno

Yeah I saw that on National Geographic's Drugs Inc. about K. Out of tons of people i've known who have used/abused K prolifically none have mentioned any of those side effects. The guy they showed seemed to use way above and beyond anything remotely recreational.

10 years ago I was fucked up 24/7.

Every six months I get a comprehensive blood screening. Everything is perfect.

I eat horribly, I don't exercise and yet the many things they test for come back perfect.

If I didn't have Crohn's I would be in perfect shape. Crohn's is likely genetic though so there is nothing I could or can do.

[MetaMan]

I would never take back any of my "friends" experiences. Drugs open your mind to so much more. People who have never taken mushrooms (myself) are totally missing out.

[mikesouth]

I actually looked into the ketamine thing and its very interesting because unlike the others which are basically synthetic cocaine the ketamine anti depressants are NOT SSRIs

and for the record the Ketamine they are usng for this is not the recreational variety, it is heavily modified to NOT have the dangerous side effects....looks like they arent available yet except on a trial basis though,

Not that Id take em Im happy with life I dont drink smoke do drugs or anything Im high on fucking girls less than half my age, scuba diving, riding my scoot and offshore fishing no drug yet even comes close to those...

[uno]

Originally Posted by mikesouth

I actually looked into the ketamine thing and its very interesting because unlike the others which are basically synthetic cocaine the ketamine anti depressants are NOT SSRIs

and for the record the Ketamine they are usng for this is not the recreational variety, it is heavily modified to NOT have the dangerous side effects....looks like they arent available yet except on a trial basis though,

Not that Id take em Im happy with life I dont drink smoke do drugs or anything Im high on fucking girls less than half my age, scuba diving, riding my scoot and offshore fishing no drug yet even comes close to those...

All those things would be incredibly awesomer on one or various drugs. Not that I'd know.

[uno]

Originally Posted by porno jew

nah at mild dose feel spacey, trippy at higher doses hard to explain.

Does it make sense if I saw "cubism" and "Tron"?

[uno]

Originally Posted by epitome

10 years ago I was fucked up 24/7.

Every six months I get a comprehensive blood screening. Everything is perfect.

I eat horribly, I don't exercise and yet the many things they test for come back perfect.

If I didn't have Crohn's I would be in perfect shape. Crohn's is likely genetic though so there is nothing I could or can do.

Everyone was a lot happier when they were doing that several times a month vs legal things like drinking now.

[uno]

Originally Posted by MetaMan

I would never take back any of my "friends" experiences. Drugs open your mind to so much more. People who have never taken mushrooms (myself) are totally missing out.

SWIM agrees.

[porno jew]

Originally Posted by uno

Does it make sense if I saw "cubism" and "Tron"?

yeah. it's a weird drug.

[uno]

shit, i meant "say"

[NetHorse]

I've also heard of people taking pure MDMA to permanently cure certain types of PTSD. If nothing else works for a person suffering, I'm all for it.

I've never shromed or done any of that shit. Not that I'm against it or anything, but I'm too old to start experimenting with it now, ha ha.

I have plenty of fun boozing on the weekends, I know people who do, (have done) drugs, (from LSD to coke or whatever) and they just don't seem the same. I think everyone else but them realize it. You can tell by their ability to hold a conversation, or how they ramble on about stupid shit and even the lives they're currently leading. That even goes for people who smoke too much weed.

It might've opened up their minds or whatever, but they sound like fucking morons now and are going nowhere in life.

[Major (Tom)]

Originally Posted by uno

Yeah I saw that on National Geographic's Drugs Inc. about K. Out of tons of people i've known who have used/abused K prolifically none have mentioned any of those side effects. The guy they showed seemed to use way above and beyond anything remotely recreational.

i know 3 heavy k users. they are all like infants now & their parents take care of them. coincidence?
no
ds

[porno jew]

Originally Posted by NetHorse

I've also heard of people taking pure MDMA to permanently cure certain types of PTSD. If nothing else works for a person suffering, I'm all for it.

I've never shromed or done any of that shit. Not that I'm against it or anything, but I'm too old to start experimenting with it now, ha ha.

I have plenty of fun boozing on the weekends, I know people who do, (have done) drugs, (from LSD to coke or whatever) and they just don't seem the same. I think everyone else but them realize it. You can tell by their ability to hold a conversation, or how they ramble on about stupid shit and even the lives they're currently leading. That even goes for people who smoke too much weed.

It might've opened up their minds or whatever, but they sound like fucking morons now.

and when i talk to guys like you it seems so boring and square. works both ways.

[NetHorse]

Originally Posted by porno jew

and when i talk to guys like you it seems so boring and square. works both ways.

You don't even know me. But yeeaaahhh man, I haven't experienced it maaann, unity with the light and the sweet colors duuude. Let's eaat some pills and stare at the wall and see if it does something man!

[Shotsie]

Originally Posted by porno jew

nah at mild dose feel spacey, trippy at higher doses hard to explain.

There's no "correct" dose of K, you either sniff too little and don't really feel it, or you sniff too much and wind up in a K hole blacked out for an hour. Plus, it's a pain in the ass to prepare, baking it on a casserole dish in the oven and all; at least when I got it, it was always liquid so it had to be cooked. I've never really done it by itself though, I was always either tripping my balls off or rolling.

[epitome]

Remember, MDMA (ecstasy) was discovered by scientists decades and decades ago and was used for couples therapy. It let them open up to one another in ways that were not previously possible.

[SlutsBukkake]

Until the US government (aka World Police) gets over itself and realizes that the war on drugs has been a gross failure not many other countries will follow suit. Portugual has been ballsy enough to go out on its own with great results

But then again, think of all the forces/officers that would be out of a job if party drugs were legalized...

[alias]

They always worked for me.

[porno jew]

Originally Posted by NetHorse

You don't even know me. But yeeaaahhh man, I haven't experienced it maaann, unity with the light and the sweet colors duuude. Let's eaat some pills and stare at the wall and see if it does something man!

see you're doing it already.

[Fletch XXX]

I stand with all my medicinal brethren

[CaptainHowdy]

I ain't an animal ...

[Operator]

Yes you are.

[BlackCrayon]

fuck ketamine. i wouldn't use that stuff. if you need more than weed to cure your depression, then you got problems. you can't stay on K for life.

[BlackCrayon]

Originally Posted by DukeSkywalker

i know 3 heavy k users. they are all like infants now & their parents take care of them. coincidence?
no
ds

same here. they were kinda goofy before but now its 10 times worse.

[uno]

Originally Posted by DukeSkywalker

i know 3 heavy k users. they are all like infants now & their parents take care of them. coincidence?
no
ds

Are they still using?

[uno]

Originally Posted by epitome

Remember, MDMA (ecstasy) was discovered by scientists decades and decades ago and was used for couples therapy. It let them open up to one another in ways that were not previously possible.

The term 'entactogen' was created for md** substances, mainly meaning 'to touch within".

http://en.wikipedia.org/wiki/Empathogen-entactogen

[MarkDeus]

Ketamine is the WORSE thing ever. It completely destroys you. Stay away from that.

[porno jew]

Originally Posted by uno

The term 'entactogen' was created for md** substances, mainly meaning 'to touch within".

http://en.wikipedia.org/wiki/Empathogen-entactogen

lame. empathogen is just fine. guess empathogen sounds too soft so they tried to harden up the word, although that itself is opposite of what mdma is and does.

[uno]

Originally Posted by porno jew

lame. empathogen is just fine. guess empathogen sounds too soft so they tried to harden up the word, although that itself is opposite of what mdma is and does.

empathogen sounds too much like pathogen i guess.

You most certainly can examine yourself more on mdma. I used to prefer to do it alone.

[epitome]

Originally Posted by DukeSkywalker

i know 3 heavy k users. they are all like infants now & their parents take care of them. coincidence?
no
ds

Something else is going on with them.

Everybody I know that used it heavily have moved on and are just fine.